Heteroditopic Binding of Magnetic Resonance Contrast Agents for Increased Relaxivity
نویسندگان
چکیده
منابع مشابه
Superparamagnetic contrast agents for magnetic resonance imaging.
SUPERPARAMAGNETIC CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING Tueng Shen Submitted to the Harvard University-Massachusetts Institute of Technology Division of Health Sciences and Technology on April 29, 1994 in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Medical Engineering/Medical Physics Abstract Magnetic resonance imaging (MRI) is a non-invasive, sens...
متن کاملmagnetic resonance imaging contrast agents: a review of literature
magnetic resonance imaging (mri) contrast agents most commonly agents used in diagnosing different diseases. several agents have been ever introduced with different peculiar characteristics. they vary in potency, adverse reaction and other specification, so it is important to select the proper agent in different situations. we conducted a systematic literature search in medline/pubmed, web of s...
متن کاملNitroxide-Based Macromolecular Contrast Agents with Unprecedented Transverse Relaxivity and Stability for Magnetic Resonance Imaging of Tumors
Metal-free magnetic resonance imaging (MRI) agents could overcome the established toxicity associated with metal-based agents in some patient populations and enable new modes of functional MRI in vivo. Herein, we report nitroxide-functionalized brush-arm star polymer organic radical contrast agents (BASP-ORCAs) that overcome the low contrast and poor in vivo stability associated with nitroxide-...
متن کاملContrast agents in dynamic contrast-enhanced magnetic resonance imaging
Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a noninvasive method to assess angiogenesis, which is widely used in clinical applications including diagnosis, monitoring therapy response and prognosis estimation in cancer patients. Contrast agents play a crucial role in DCE-MRI and should be carefully selected in order to improve accuracy in DCE-MRI examination. Over the past...
متن کاملStrategies for Target-Specific Contrast Agents for Magnetic Resonance Imaging.
This review describes recent research efforts focused on increasing the specificity of contrast agents for proton magnetic resonance imaging (MRI). Contrast agents play an indispensable role in MRI by enhancing the inherent contrast of images; however, the non-specific nature of current clinical contrast agents limits their usefulness. This limitation can be addressed by conjugating contrast ag...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Angewandte Chemie International Edition
سال: 2011
ISSN: 1433-7851
DOI: 10.1002/anie.201007689